This video via Trifonic (Brian Trifon), takes a look at techniques for creating filthy bass and lead sounds using Logic’s EXS24 sampler, in combination with the old-school hardware sampler, EMu E6400.
“If you don’t use Logic and don’t plan on purchasing an EMu unit, fear not,” notes Trifon. “The principles here are surely applicable to whatever you’ve got in your studio.”
I tend to have a lot of tangled cables in my studio, but not many twisted leads.